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Going self-employed as a locum

Updated Sun, 14 Jun 2026 1 min read

Most locum pharmacists work as sole traders — self-employed individuals invoicing pharmacies directly. Here's the general shape of getting set up.

Register with HMRC#

If you earn money outside of PAYE employment, you usually need to register as self-employed with HMRC and file a Self Assessment tax return each year. There are deadlines for registering after you start trading — check the current dates on GOV.UK.

Keep records#

  • Keep a record of every shift: date, pharmacy, rate, hours and mileage. (That's what the shift log here is for.)
  • Keep copies of the invoices you issue and note when each is paid.
  • Hold on to receipts for legitimate business expenses (professional indemnity insurance, GPhC fees, mileage, professional subscriptions).

Set money aside for tax#

You'll typically owe Income Tax and National Insurance on your profits. A common habit is to move a portion of each payment into a separate account so the tax bill isn't a surprise. The exact percentage depends on your circumstances.

Where to get proper advice#

This is general information only. For your own situation, speak to a qualified accountant and check the official guidance on GOV.UK and HMRC.

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General information only — not financial, tax, or legal advice. Always check official sources (GOV.UK, HMRC, GPhC) and consult a qualified professional about your own situation.